During a chase inside a museum, Tom and Jerry find an ancient magical compass and end up being transported through time. Lost in a distant era, they will need to work together to find a way back home.

Four years after the events of Spider-Man: No Way Home, Peter Parker is no more and Spider-Man is at the top of his game keeping New York City safe. Things are going well until an unusual trail of crimes pulls Spider-Man into a web of mystery larger than he's ever faced before. In order to take on what's ahead, Spider-Man not only needs to be at the top of his physical and mental game, but he must also be prepared to face the repercussions of his past!