Superman, a cub reporter in Metropolis, embarks on a journey to reconcile his Kryptonian heritage with his human upbringing as Clark Kent.

After the underlying tech for M3GAN is stolen and misused by a powerful defense contractor to create a military-grade weapon known as Amelia, M3GAN's creator Gemma realizes that the only option is to resurrect M3GAN and give her a few upgrades, making her faster, stronger, and more lethal.

Against the vibrant backdrop of a 1960s-inspired, retro-futuristic world, Marvel's First Family is forced to balance their roles as heroes with the strength of their family bond, while defending Earth from a ravenous space god called Galactus and his enigmatic Herald, Silver Surfer.